Savant syndrome () is a rare condition in which someone with significant mental disabilities demonstrates certain abilities far in excess of average. The skills that savants excel at are generally related to memory. This may include rapid calculation, artistic ability, map making, or musical ability. Usually, only one exceptional skill is present.

Those with the condition generally have a neurodevelopmental disorder such as autism spectrum disorder or have a brain injury. About half of cases are associated with autism, and these individuals may be known as "autistic savants". While the condition usually becomes apparent in childhood, some cases develop later in life. It is not recognized as a mental disorder within the DSM-5.

Savant syndrome is estimated to affect around one in a million people. The condition affects more males than females, at a ratio of 6:1. The first medical account of the condition was in 1783. Among those with autism, 1 in 10 to 1 in 200 have savant syndrome to some degree. It is estimated that there are fewer than a hundred prodigious savants, with skills so extraordinary that they would be considered spectacular even for a non-impaired person, currently living.